The immune system has evolved over millions of years as our body’s defense system against pathologic invaders. This learning program is designed to introduce you to the basic functions of the immune system. The program begins with an overview of the types of immune responses: innate immunity as well as antibody-mediated and cell-mediated acquired immunity. You will then learn about ways in which the body can change and shape the immune response, as well as the autoimmune responses that can occur when the system for recognizing pathogens malfunctions. Finally, you will learn about the specific mechanisms the immune system uses to recognize and destroy tumor cells.
Upon completion of this learning program you will be able to::
Describe innate immunity and its major components.
Define acquired immunity and recall the basics on antigens and antigen-presenting cells.
Identify the different processes and cells involved in antibody-mediated immunity and in cell-mediated immunity.
Describe the mechanisms by which the body can modulate the immune response.
Recognize the basic mechanisms of autoimmune disorders and hypersensitivity reactions.
Summarize the mechanisms of the immune response to tumors
Types Of Immune Response
Popup: Physical And Chemical Barriers
Popup: Antimicrobial Proteins
Popup: Innate Immune Cells
Major Histocompatibility Complexes
The Major Histocompatibility Complex Class I
Animated Popup: Role Of Mhc-i Molecules In The Immune Response
The Major Histocompatibility Complex Class II
Slideshow: Polymeric Antibodies
Popup: Immunoglobulin G
Popup: Immunoglobulin A
Popup: Immunoglobulin M
Popup: Immunoglobulin D
Popup: Immunoglobulin E
B-cell Differentiation And Antibody Production
The Complement System
Slideshow: The 5 Steps Of The Complement Cascade
The Role Of Mhc In Cell-mediated Immunity
Cd4+ T Cells
Cd8+ T Cells
Slideshow: Target Cell Destruction By Cd8+ T Cells